Scientific Papers

  • Groß CJ, Mishra R, Schneider KS, Médard G, Wettmarshausen J, Dittlein DC, Shi H, Gorka O, Koenig PA, Fromm S, Magnani G, Ćiković T, Hartjes L, Smollich J, Robertson AA, Cooper MA, Schmidt-Supprian M, Schuster M, Schroder K, Broz P, Traidl-Hoffmann C, Beutler B, Kuster B, Ruland J, Schneider S, Perocchi F, Groß O (2016). K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria. Immunity. 18;45(4):761-773

  • Kishi S, Campanholle G, Gohil VM, Perocchi F, Brooks CR, Morizane R, Sabbisetti V, Ichimura T, Mootha VK, Bonventre JV. (2015) Meclizine Preconditioning Protects the Kidney Against Ischemia-Reperfusion Injury. EBioMedicine 2(9):1090-101.

  • Cheng Y, Perocchi F (2015). ProtPhylo: identification of protein-phenotype and protein-protein functional associations via phylogenetic profiling. Nucleic Acids Res. 2015 Jul 1;43(W1):W160-8.

  • Cheng Y, Perocchi F (2015). Prediction of mitochondrial protein function by comparative physiology and phylogenetic profiling. Methods Mol Biol.

  • Jastroch M, Keipert S, Perocchi F (2014). From explosives to physiological combustion: Next generation chemical uncouplers. Mol Metab. 

  • Rorbach J, Boesch P, Gammage PA, Nicholls TJ, Pearce SF, Patel D, Hauser A, Perocchi F, Minczuk M (2014). MRM2 and MRM3 are involved in biogenesis of the large subunit of the mitochondrial ribosome. Mol Biol Cell. 25(17):2542-55.

  • Csordas G, Golenar T, Seifert EL, Kamer KJ, Sancak Y, Perocchi F, Moffat C, Weaver D, de la Fuente Perez S, Bogorad R, Koteliansky V, Adijanto J, Mootha VK, and Hajnoczky J (2013). MICU1 Controls Both the Threshold and Cooperative Activation of the Mitochondrial Ca2+ Uniporter. Cell Metabolism.

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  • Dolga AM, Netter MF, Perocchi F, Doti N, Meissner L, Tobaben S, Grohm J, Zischka H, Plesnila N, Decher N, Culmsee C (2013). Mitochondrial Small Conductance SK2 Channels Prevent Glutamate-induced Oxytosis and Mitochondrial Dysfunction. J Biol Chem. 288(15):10792-804.

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  • Baughman JM*, Perocchi F*, Girgis HS, Plovanich M, Belcher-Timme CA, Sancak Y, Bao XR, Strittmatter L, Goldberger O, Bogorad RL, Koteliansky V, Mootha VK (2011). Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature. 476(7360):341-5.

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  • Perocchi F, Gohil VM, Girgis HS, Bao XR, McCombs JE, Palmer AE, Mootha VK (2010). MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake. Nature. 467(7313):291-6.

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  • Gohil VM*, Sheth SA*, Nilsson R, Wojtovich AP, Lee JH, Perocchi F, Chen W, Clish CB, Ayata C, Brookes PS, Mootha VK (2010). Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis. Nature Biotechnology. 28(3):249-55.

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  • Gagneur J, Sinha H, Perocchi F, Bourgon R, Huber W, Steinmetz LM (2009). Genome-wide allele- and strand-specific expression profiling. Molecular Systems Biology. 5:274.

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  • Xu Z*, Wei W*, Gagneur J, Perocchi F, Clauder-Münster S, Camblong J, Guffanti E, Stutz F, Huber W, Steinmetz LM (2009). Bidirectional promoters generate pervasive transcription in yeast. Nature. 457(7232):1033-7.

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  • Perocchi F*, Mancera E*, Steinmetz LM (2008). Systematic screens for human disease genes, from yeast to human and back. Molecular Biosystems. 4(1):18-29.

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  • Perocchi F*, Xu Z*, Clauder-Münster S, Steinmetz LM (2007). Antisense artifacts in transcriptome microarray experiments are resolved by actinomycin D. Nucleic Acids Research. 35(19):e128.

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  • Perocchi F, Jensen LJ, Gagneur J, Ahting U, von Mering C, Bork P, Prokisch H, Steinmetz LM (2006). Assessing systems properties of yeast mitochondria through an interaction map of the organelle. PLoS Genetics. 2(10):e170.

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